Advancements In Glycosylation Of Hesperidin To Boost Aspects In Functional Food Industry

Hesperidin is a disaccharide derivative and flavonoid which is largely extracted from citrus fruits such as lemon, orange, lime, grapefruit etc. Hesperidin finds considerable application as an antioxidant, anti-inflammatory, flavour enhancing plant pigment in pharmaceutical industry, food industry, dietary supplements, cosmetic industry and others.  Hesperidin has been observed to decrease capillary permeability and fragility along with other diverse physiological activities that includes improvements in poor circulation, hypertension and hyperlipidaemia. However, owing to their low solubility in water, their application was limited earlier in functional foods. Researchers have overcome this issue by performing glycosylation of hesperidin to produce glucosyl hesperidin that is 100,000 times more soluble than hesperidin. This has offered the functional food manufacturers to largely utilize this compound in food applications.

Growth in functional food market has surged the consumption of hesperidin in food industry. Hesperidin market has been anticipated to show growth rate of 6.8% during 2019-2026. According to the Institute of Food Technologists, global functional food sales has boosted to about $63.3 billion as of 2017 rising from about $55.1 billion in 2015. Moreover, according to the new case study by European Association of Fruit Juice Industry (AIJN), hesperidin found in orange juice may considerably help in the reduction of blood pressure and other risk factors associated to cardiovascular diseases. This has raised the consumption of hesperidin among large consumer base suffering from rising blood pressure problem. According to the world health organization as of year 2016, 1.1 billion people suffered from the problem of raised blood pressure.

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Demand for sweetening ingredient in pharma to foster growth in hesperidin market

Other than food manufacturing, hesperidin is also finding its application in pharmaceutical and cosmeceutical industry. In pharma manufacturing it is largely utilized to reduce the bitter taste of medicine. Moreover, hesperidin can be converted to dihydrochalcone that are utilized as a low calorie sweetener that is suitable for obese and diabetic patients. Furthermore, hesperidin finds potential to prepare drug for myocardial infraction and atherosclerosis. Surging growth in pharmaceutical production is expected to promote the growth in demand of sweetening agent such as hesperidin specifically in research and development of this compound specifically in North America region. According to the International Federation of Pharmaceutical Manufacturers & Associations, global pharmaceutical market is projected to reach nearly $1,430 billion by the year 2020. As of 2017 facts from the federation, research based pharmaceutical industry spends approximately $149.8 billion on research and development per year. Moreover, United states pharmaceutical share is expected to rise by about 41% in 2019 from 40.3% in 2015. This growth is expected to rise the consumption of hesperidin in pharmaceutical industry promoting swift growth in the global hesperidin market during the forecast years 2019-2026.